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  • Emily M. McWilliams, Christopher R. Lucas, Timothy Chen, Bonnie K. Harrington, Ronni Wasmuth, Amanda Campbell, Kerry A. Rogers, Carolyn M. Cheney, Xiaokui Mo, Leslie A. Andritsos, Farrukh T. Awan, Jennifer Woyach, William E. Carson III,Jonathan Butchar, Susheela Tridandapani, Erin Hertlein, Carlos E. Castro, Natarajan Muthusamy, and John C. Byrd, "Anti-BAFF-R Antibody VAY-736 Demonstrates Promising Pre-Clinical Activity in CLL and Enhances Effectiveness of Ibrutinib." Blood Advances. (2019) Accepted
  • Halley, P.D., Patton, R.A., Chowdhury, A., Byrd, J.C., Castro, C.E., "Low-cost, simple, and scalable self-assembly of DNA origami nanostructures." in revision

  • Zhao, D., Le, J., Darcy, M., Poirier, M.G., Castro, C.E., Bundschuh, R., "Quantitative Modeling of Concomitant Nucleosome Unwrapping." in revision 


  • Ke, Y., Castro, C.E., Choi, J.H., "Structural DNA Nanotechnology: Artificial Nanostructures for Biomedical Research." Annual Review of Biomedical Engineering. (2018) link
  • Huang, C.M., Kucinic, A., Le, J.V., Castro, C.E.,* and Su, H.-J.,* "Uncertainty Quantification of a DNA Origami Mechanism Using a Coarse-Grained Model and Kinematic Variance Analysis." Nanoscale. (2018) link
  • Zhou, L., Marras, A.E., Huang, C-M., Castro, C.E.,* Su, H-J.,* "Paper origami-inspred Design and Actuation of DNA Nanorobots with Complex Motions." Small. (2018) link
  • Marras, A.E., Shi, Ze, Lindell, M., Zhou, L., Su, H-J., Arya, G.,* Castro, C.E.,* "Cation-activated avidity for rapid reconfiguration of DNA nanodevices." ACS Nano. (2018). link

  • Lauback, S., Mattioli, K.R., Marras, A.E., Armstrong, M., Rudibaugh, T., Sooryakumar, R.,* Castro, C.E.,* "Real-time Magnetic Control of DNA Nanodevices." Nature Communicationslink
  • Lei, D., Marras, A.E., Liu, J., Huang, C-M., Zhou, L., Castro, C.E., Su, H-J., Ren, G., "3D Structural Dynamics of DNA origami Mechanisms and Machines Using Individual Particle Electron Tomography." Nature Communications. link


  • Wang, P., Chatterjee, G., Yan, H., LaBean, T.H., Turberfield, A.J., Castro, C.E., Seelig, G., and Ke, Y. Practical aspects of structural and dynamic DNA nanotechnology. MRS Bulletin. link
  • Castro,C.E., Dietz, H., Högberg, B. DNA origami devices for molecular-scale precision measurements. MRS Bulletinlink
  • Akbari, E., Mollica, M., Lucas, C.R., Bushman, S., Patton, R.A., Shahhosseini, M., Song, J.W., Castro, C.E., "Engineering Cell Surface Function with DNA Origami." Advanced Materials. link 
  • Hudoba, M., Luo, Y., Zacharias, A., Poirier, M.G., Castro, C.E., "A Dynamic DNA origami device for measuring compressive depletion forces." ACS Nano. link
  • Shi, Z., Castro, C.E., Arya, G. "Conformational Dynamics of Mechanically Compliant DNA Nanostructures from Coarse-Grained Molecular Dynamics Simulations." ACS Nano link
  • Zhou, L., Su, H-J., Marras, C-M., Castro, C.E., "Projection kinematic analysis of DNA origami mechanisms based on a two-dimensional TEM image." Mechanisms and Machine Theory. link
  • Liang, B., Nagarajan, A., Hudoba, M.W., Alvarez, R., Castro, C.E., Soghrati, S., "Automated Quantification of the Impact of Defects on the Mechanical Behavior of DNA Origami Nanoplates." ASME Journal of Biomechanical Engineering. link


  • Le, J., Luo, Y., Darcy, M., Lucas, C.R., Goodwin, M., Poirier, M.G., Castro, C.E., "Probing Nucleosome Stability with a DNA Origami Nanocaliper." ACS Nano. link
  • Marras, A.E., Zhou, L., Kolliopoulos, V., Su, H., Castro, C.E., "Directing folding pathways for multi-component DNA origami nanostructures with complex topology." New Journal of Physics. link
  • Kearney, C.J., Lucas, C.R., O’Brien, F.J., Castro, C.E., "DNA Origami: Folded DNA-Nanodevices That Can Direct and Interpret Cell Behavior." Advanced Materials. link
  • Halley, P.D.*, Lucas, C.R.*, McWilliams, E.M., Webber, M.J., Patton, R., Kural, C., Lucas, D.M., Byrd, J.C., Castro, C.E. "Daunorubicin-Loaded DNA Origami Nanostructures Circumvent Drug Resistance Mechanisms in a Leukemia Model." Smalllink (*co-first author)


  • Zhou, L., Marras, A.E., Castro, C.E., Su, H. "Design and Modeling of Compliant DNA Origami Mechanisms." Journal of Mechanisms and Robotics. link
  • Zhou, L., Marras, A.E., Su, H., Castro, C.E. "Direct design of an energy landscape with bistable DNA origami mechanisms." Nano Letters. link
  • Castro, C.E., Su, H., Marras, A.E., Zhou, L., Johnson, J. "Mechanical Design of DNA nanostructures." Nanoscale. link
  • Marras, A.E., Zhou, L., Su, H., Castro, C.E. "Programmable motion of DNA origami mechanisms." Proceedings of the National Academy of Sciences. link (pdf)


  • Gupta, C., Liao, W. C., Gallego-Perez, D., Castro, C. E., & Lee, L. J. "DNA translocation through short nanofluidic channels under asymmetric pulsed electric field." Biomicrofluidics. link
  • Zhou, L., Marras, A.E., Su, H., Castro, C.E. "DNA origami compliant nanostructures with tunable mechanical properties." ACS Nanolink


  • Wu, Y., Kwak, K.J., Agarwal, K., Marras, A.E., Wang, C., Mao, Y, Huang, X., Ma, J., Yu, B., Lee, R. Vachani, A., Marcucci, G., Byrd, J., Muthusamy, N., Otterson, G., Huang, K., Castro, C.E., Paulaitis, M., Nano-Sinkam, S.P., Lee, L.J., "Detection of Extracellular RNAs in Cancer and Viral Infection via Tethered Cationic Lipoplex Nanoparticles Containing Molecular Beacons." Analytical Chemistry. link
  • Nguyen, V., Lilly, B., Castro, C.E. "The exoskeletal structure and tensile loading behavior of an ant neck joint." Journal of Biomechanics. link (pdf)


  • Marras, A.E., Su, J., Castro, C. E. Design of DNA Origami Machines and Mechanisms. ASME International Mechanical Engineering Congress and Exposition (IMECE 2012), Houston, Texas, Nov 9-15
  • Su, H., Castro, C.E., Marras, A.E., Hudoba, M. Design and Fabrication of DNA Origami Mechanisms and Machines. Second ASME/IEE International Conference on Reconfigurable Mechanisms and Robots (ReMAR 2012), Tianjin, China, July 9-11, 2012


  • Castro, C.E., Kilchherr F., Kim, D., Lin Shiao, E., Wauer, T., Wortmann, P., Bathe, M., Dietz, HA, "Primer to Scaffolded DNA Origami." Nature Methods. link
  • Castro, C.E., Dong, J., Lindquist, S., Boyce, M.C., Lang, M.J., "Physical Properties of Polymorphic Prion Proteins." Biophysical Journal
  • Jungmann, R., Scheible, M., Kuzyk, A., Pardatscher, G., Castro, C.E., and Simmel F.C., "DNA origami-based nanoribbons: assembly, length distribution, and twist." Nanotechnology
  • Wang, L., Castro, C.E., and Boyce, M.C. Growth strain-induced membrane morphology of white blood cells. Soft Matter. 7:11319-11324 (2011)
  • Tam, J.M., Castro, C.E., Heath, R.J., Mansour, M.K., Cardenas, M.L., Xavier, R., Lang, M.J., Vyas, J.M. (2011) Use of an Optical Trap for Study of Host-Pathogen Interactions for Dynamic Live Cell Imaging J Vis Exp; doi: 10.3791/3123.


  • Tam, J., Castro, C.E., Heatsh, R.J., Cardenas, M.J., Xavier, R., Lang, M.J., Vyas, J.M., "Control and Manipulation of Pathogens with an Optical Trap for Live Cell Imaging of Intercellular Interactions." PLoS One
  • Dong, J., Castro, C.E., Boyce, M.C., Lang, M.J., and Lindquist, S., "Optical trapping with high forces reveals unexpected behaviors of prion fibrils." Nature Structural & Molecular Biology
  • Palmer, J.S., Castro, C.E., Arslan, M., Boyce, M.C. Constitutive Models for the Force- Extension Behavior for Biological Filaments. Proceedings of the IUTAM symposium on Molecular, Cellular, and Tissue Biomechanics. IUTAM Bookseries, Volume 16


  • Kim, S.T., Takeuchi, K., Zhen-Yu, J.S., Touma, M., Castro, C.E., Fahmy, A., Vibhuti, D., Kappes, D., Lang, M.J., Wagner, G., Reinherz, E., "The αβ T cell receptor is an anisotropic mechanosensor." Journal of Biological Chemistry


  • Villarreal, M.G., Sánchez Peña, M.L., Castro, C.E., Castro, J.M., Cabrera-Rios, M. Using data clustering to aid the solution of multiple criteria optimization problems through data envelopment analysis, Intelligent Data Analysis – An International Journal 12(1):89-101



  • Brau, R. Ferrer, J.M., Lee, H., Castro, C.E., Tam, B.K., Tarsa, P.B., Matsudaira, P, Boyce, M.C., Kamm, R.D., Lang, M.J. Passive and active microrheology with optical tweezers, Journal of Optics A: Pure and Applied Optics; 9: S103-S112
  • Castro, C.E., Cabrera Rios, M., Lilly, B., Castro, J.M. Multiple Criteria Optimization with Variability Considerations in Injection Molding. Polymer Engineering and Science. 47(4):400-409