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  • Halley, P.D., Patton, R.A., Chowdhury, A., Byrd, J.C., Castro, C.E., "Low-cost, simple, and scalable self-assembly of DNA origami nanostructures." submitted
  • Zhao, D., Le, J., Darcy, M., Poirier, M.G., Castro, C.E., Bundschuh, R., "Quantitative Modeling of Concomitant Nucleosome Unwrapping." submitted 
  • Huang, C.M., Kucinic, A., Le, J.V., Castro, C.E.,* and Su, H.-J.,* "Uncertainty Quantification of a DNA Origami Mechanism Using a Coarse-Grained Model and Kinematic Variance Analysis." under review
  • Zhou, L., Marras, A.E., Huang, C-M., Castro, C.E.,* Su, H-J.,* "Paper origami-inspred Design and Actuation of DNA Nanorobots with Complex Motions." under review  
  • Marras, A.E., Shi, Ze, Lindell, M., Zhou, L., Su, H-J., Arya, G.,* Castro, C.E.,* "Cation-activated avidity for rapid reconfiguration of DNA nanodevices." ACS Nano, in press (2018). link

  • Lauback, S., Mattioli, K.R., Marras, A.E., Armstrong, M., Rudibaugh, T., Sooryakumar, R.,* Castro, C.E.,* "Real-time Magnetic Control of DNA Nanodevices." Nature Communicationslink
  • Lei, D., Marras, A.E., Liu, J., Huang, C-M., Zhou, L., Castro, C.E., Su, H-J., Ren, G., "3D Structural Dynamics of DNA origami Mechanisms and Machines Using Individual Particle Electron Tomography." Nature Communications. link


  • Wang, P., Chatterjee, G., Yan, H., LaBean, T.H., Turberfield, A.J., Castro, C.E., Seelig, G., and Ke, Y. Practical aspects of structural and dynamic DNA nanotechnology. MRS Bulletin. link
  • Castro,C.E., Dietz, H., Högberg, B. DNA origami devices for molecular-scale precision measurements. MRS Bulletinlink
  • Akbari, E., Mollica, M., Lucas, C.R., Bushman, S., Patton, R.A., Shahhosseini, M., Song, J.W., Castro, C.E., "Engineering Cell Surface Function with DNA Origami." Advanced Materials. link 
  • Hudoba, M., Luo, Y., Zacharias, A., Poirier, M.G., Castro, C.E., "A Dynamic DNA origami device for measuring compressive depletion forces." ACS Nano. link
  • Shi, Z., Castro, C.E., Arya, G. "Conformational Dynamics of Mechanically Compliant DNA Nanostructures from Coarse-Grained Molecular Dynamics Simulations." ACS Nano link
  • Zhou, L., Su, H-J., Marras, C-M., Castro, C.E., "Projection kinematic analysis of DNA origami mechanisms based on a two-dimensional TEM image." Mechanisms and Machine Theory. link
  • Liang, B., Nagarajan, A., Hudoba, M.W., Alvarez, R., Castro, C.E., Soghrati, S., "Automated Quantification of the Impact of Defects on the Mechanical Behavior of DNA Origami Nanoplates." ASME Journal of Biomechanical Engineering. link


  • Le, J., Luo, Y., Darcy, M., Lucas, C.R., Goodwin, M., Poirier, M.G., Castro, C.E., "Probing Nucleosome Stability with a DNA Origami Nanocaliper." ACS Nano. link
  • Marras, A.E., Zhou, L., Kolliopoulos, V., Su, H., Castro, C.E., "Directing folding pathways for multi-component DNA origami nanostructures with complex topology." New Journal of Physics. link
  • Kearney, C.J., Lucas, C.R., O’Brien, F.J., Castro, C.E., "DNA Origami: Folded DNA-Nanodevices That Can Direct and Interpret Cell Behavior." Advanced Materials. link
  • Halley, P.D.*, Lucas, C.R.*, McWilliams, E.M., Webber, M.J., Patton, R., Kural, C., Lucas, D.M., Byrd, J.C., Castro, C.E. "Daunorubicin-Loaded DNA Origami Nanostructures Circumvent Drug Resistance Mechanisms in a Leukemia Model." Smalllink (*co-first author)


  • Zhou, L., Marras, A.E., Castro, C.E., Su, H. "Design and Modeling of Compliant DNA Origami Mechanisms." Journal of Mechanisms and Robotics. link
  • Zhou, L., Marras, A.E., Su, H., Castro, C.E. "Direct design of an energy landscape with bistable DNA origami mechanisms." Nano Letters. link
  • Castro, C.E., Su, H., Marras, A.E., Zhou, L., Johnson, J. "Mechanical Design of DNA nanostructures." Nanoscale. link
  • Marras, A.E., Zhou, L., Su, H., Castro, C.E. "Programmable motion of DNA origami mechanisms." Proceedings of the National Academy of Sciences. link (pdf)


  • Gupta, C., Liao, W. C., Gallego-Perez, D., Castro, C. E., & Lee, L. J. "DNA translocation through short nanofluidic channels under asymmetric pulsed electric field." Biomicrofluidics. link
  • Zhou, L., Marras, A.E., Su, H., Castro, C.E. "DNA origami compliant nanostructures with tunable mechanical properties." ACS Nanolink


  • Wu, Y., Kwak, K.J., Agarwal, K., Marras, A.E., Wang, C., Mao, Y, Huang, X., Ma, J., Yu, B., Lee, R. Vachani, A., Marcucci, G., Byrd, J., Muthusamy, N., Otterson, G., Huang, K., Castro, C.E., Paulaitis, M., Nano-Sinkam, S.P., Lee, L.J., "Detection of Extracellular RNAs in Cancer and Viral Infection via Tethered Cationic Lipoplex Nanoparticles Containing Molecular Beacons." Analytical Chemistry. link
  • Nguyen, V., Lilly, B., Castro, C.E. "The exoskeletal structure and tensile loading behavior of an ant neck joint." Journal of Biomechanics. link (pdf)


  • Marras, A.E., Su, J., Castro, C. E. Design of DNA Origami Machines and Mechanisms. ASME International Mechanical Engineering Congress and Exposition (IMECE 2012), Houston, Texas, Nov 9-15
  • Su, H., Castro, C.E., Marras, A.E., Hudoba, M. Design and Fabrication of DNA Origami Mechanisms and Machines. Second ASME/IEE International Conference on Reconfigurable Mechanisms and Robots (ReMAR 2012), Tianjin, China, July 9-11, 2012


  • Castro, C.E., Kilchherr F., Kim, D., Lin Shiao, E., Wauer, T., Wortmann, P., Bathe, M., Dietz, HA, "Primer to Scaffolded DNA Origami." Nature Methods. link
  • Castro, C.E., Dong, J., Lindquist, S., Boyce, M.C., Lang, M.J., "Physical Properties of Polymorphic Prion Proteins." Biophysical Journal
  • Jungmann, R., Scheible, M., Kuzyk, A., Pardatscher, G., Castro, C.E., and Simmel F.C., "DNA origami-based nanoribbons: assembly, length distribution, and twist." Nanotechnology
  • Wang, L., Castro, C.E., and Boyce, M.C. Growth strain-induced membrane morphology of white blood cells. Soft Matter. 7:11319-11324 (2011)
  • Tam, J.M., Castro, C.E., Heath, R.J., Mansour, M.K., Cardenas, M.L., Xavier, R., Lang, M.J., Vyas, J.M. (2011) Use of an Optical Trap for Study of Host-Pathogen Interactions for Dynamic Live Cell Imaging J Vis Exp; doi: 10.3791/3123.


  • Tam, J., Castro, C.E., Heatsh, R.J., Cardenas, M.J., Xavier, R., Lang, M.J., Vyas, J.M., "Control and Manipulation of Pathogens with an Optical Trap for Live Cell Imaging of Intercellular Interactions." PLoS One
  • Dong, J., Castro, C.E., Boyce, M.C., Lang, M.J., and Lindquist, S., "Optical trapping with high forces reveals unexpected behaviors of prion fibrils." Nature Structural & Molecular Biology
  • Palmer, J.S., Castro, C.E., Arslan, M., Boyce, M.C. Constitutive Models for the Force- Extension Behavior for Biological Filaments. Proceedings of the IUTAM symposium on Molecular, Cellular, and Tissue Biomechanics. IUTAM Bookseries, Volume 16


  • Kim, S.T., Takeuchi, K., Zhen-Yu, J.S., Touma, M., Castro, C.E., Fahmy, A., Vibhuti, D., Kappes, D., Lang, M.J., Wagner, G., Reinherz, E., "The αβ T cell receptor is an anisotropic mechanosensor." Journal of Biological Chemistry


  • Villarreal, M.G., Sánchez Peña, M.L., Castro, C.E., Castro, J.M., Cabrera-Rios, M. Using data clustering to aid the solution of multiple criteria optimization problems through data envelopment analysis, Intelligent Data Analysis – An International Journal 12(1):89-101



  • Brau, R. Ferrer, J.M., Lee, H., Castro, C.E., Tam, B.K., Tarsa, P.B., Matsudaira, P, Boyce, M.C., Kamm, R.D., Lang, M.J. Passive and active microrheology with optical tweezers, Journal of Optics A: Pure and Applied Optics; 9: S103-S112
  • Castro, C.E., Cabrera Rios, M., Lilly, B., Castro, J.M. Multiple Criteria Optimization with Variability Considerations in Injection Molding. Polymer Engineering and Science. 47(4):400-409